Articles Morrison C, Jones M, Blackwell A, Vuylsteke A. Electronic Patient Record use during ward rounds: a qualitative study of interaction between medical staff. Critical Care Forum 2008;12(6):R148. Berman M, Tsui S, Vuylsteke A, Snell A, Colah S, Latimer R, Hall R, Arrowsmith JE, Kneeshaw J, Klein AA, Jenkins DP. Successful extracorporeal membrane oxygenation (ECMO) support after pulmonary thromboendarterectomy (PTE). Annals of Thoracic Surgery 2008;84(4):1261-1267. Klein AA, Nashef SAM, Sharples L, Bottrill F, Dyer M, Armstrong J, Vuylsteke A. A randomized controlled trial of cell salvage in routine cardiac surgery. Anesthesia & Analgesia 2008;107(5):1487-95. Thomson B, Tsui SS, Dunning J, Goodwin A, Vuylsteke A, Latimer R, Pepke-Zaba J, Jenkins DP. Pulmonary endarterectomy is possible and effective without the use of complete circulatory arrest--the UK experience in over 150 patients. European Journal of Cardiothoracic Surgery 2008;33(2):157-63. Pubmed ID=18077177 Choong CK, Gerrard C, Goldsmith KA, Dunningham H, Vuylsteke A
. Delayed re-exploration for bleeding after coronary artery bypass surgery results in adverse outcomes. European Journal of Cardiothoracic Surgery 2007;31(5):834-8. Pubmed ID=17360191 more... Dunningham H, Borland C, Bottrill F, Gordon D, Vuylsteke A. Modelling lung and tissue diffusion using a membrane oxygenator circuit. Perfusion 2007;22(4):231-8. Pubmed ID=18181510 Mangano DT, Miao Y, Vuylsteke A, Tudor IC, Juneja R, Filipescu D, Hoeft A, Fontes ML, Hillel Z, Ott E, Titov T, Dietzel C, Levin J; Investigators of The McSPI Research Group; IREF. Mortality associated with aprotinin during 5 years following coronary artery bypass graft surgery. Journal of the American Medical Association 2007;297(5):471-9. Pubmed ID=17284697 more... Drain AJ, Sivasothy P, Nashef S, Wells FC, Vuylsteke A. Do you know a pneumo?. Journal of Cardiothoracic & Vascular Anesthesia 2006;20(5):748-50. Pubmed ID=17023302 Vuylsteke A, Saravanan P, Gerrard C, Cafferty F. The impact of administration of tranexamic acid in reducing the use of red blood cells and other blood products in cardiac surgery
. BMC Anesthesiology 2006;6:9. Pubmed ID=16942621 more... De Silva RJ, Vuylsteke A, Fritchley SJ, Trull AK, Dunning JJ, Wallwork J. APT070 inhibits complement activation during in vitro cardiopulmonary bypass. European Journal of Cardiothorac Surgery 2006;30(1):72-6. Pubmed ID=16723247 more... Drain AJ, Gerrard C, Ferguson JI, Cafferty F, Gurprashad R, Vuylsteke A. Does body mass index (BMI) affect cost in cardiac surgery? 'A pound (pound) for pound (lb) analysis'. Interactive Cardiovascular & Thoracic Surgery 2006;5(3):282-4. Pubmed ID=17670569 more... Borland C, Dunningham H, Bottrill F, Vuylsteke A. Can a membrane oxygenator be a model for lung NO and CO transfer?. Journal of Applied Physiology 2006;100(5):1527-38. Pubmed ID=16397061 more... Cornelissen J, Kirtland S, Lim E, Goddard M, Bellm S, Sheridan K, Large S, Vuylsteke A
. Biological efficacy of low against medium dose aspirin regimen after coronary surgery: analysis of platelet function. Thrombosis & Haemostasis 2006;95(3):476-82. Pubmed ID=16525576 more... Webb ST, Patil V, Vuylsteke A. Anaesthesia for non-cardiac surgery in patient with Becker's muscular dystrophy supported with a left ventricular assist device. European Journal of Anaesthesiology 2005;24(7):640-2. Pubmed ID=17632873 Ali ZA, Lim E, Motalleb-Zadeh R, Ali AA, Callaghan CJ, Gerrard C, Vuylsteke A, Foweraker J, Tsui S. Allogenic blood transfusion does not predispose to infection after cardiac surgery. Annals of Thoracic Surgery 2004;78(5):1542-6. Pubmed ID=15511427 more... Leather HA, Vuylsteke A, Bert C, M'Fam W, Segers P, Sergeant P, Vandermeersch E, Wouters PF. Evaluation of a new continuous cardiac output monitor in off-pump coronary artery surgery. Anaesthesia 2004;59(4):385-9. Pubmed ID=15023110 more... Cheng DC, Mazer CD, Martineau R, Ralph-Edwards A, Karski J, Robblee J, Finegan B, Hall RI, Latimer R, Vuylsteke A. A phase II dose-response study of hemoglobin raffimer (Hemolink) in elective coronary artery bypass surgery
. Journal of Thoracic & Cardiovascular Surgery 2004;127(1):79-86. Pubmed ID=14752416 more... De Silva RJ, Dunningham H, Vuylsteke A. The use of nitric oxide as part of the sweep gas infusion during cardiopulmonary bypass. Journal of Cardiothoracic & Vascular Anesthesia 2003;17(6):783-4. Pubmed ID=14689430 Powroznyk AV, Vuylsteke A, Naughton C, Misso SL, Holloway J, Jolin-Mellgård A, Latimer RD, Nordlander M, Feneck RO. Comparison of clevidipine with sodium nitroprusside in the control of blood pressure after coronary artery surgery. European Journal of Anaesthesiology 2003;20(9):697-703. Pubmed ID=12974590 more... Vuylsteke A, Gerrard C. OPCAB: heparin reversal?. J Cardiothorac Vasc Anesth 2003;17(4):447-51. Pubmed ID=15232827 Murali B, Vuylsteke A, Latimer RD. Anaesthetic Management of the Multi-organ Donor. Annals of Cardiac Anaesthesia 2003;6(1):31-4. Pubmed ID=17827589 Mangano DT; Multicenter Study of Perioperative Ischemia Research Group (incl. Vuylsteke A, Latimer RD). Aspirin and mortality from coronary bypass surgery. New England Journal of Medicine 2002;347(17):1309-17. Pubmed ID=12397188 more... Guo X, Kuzumi E, Charman SC, Vuylsteke A. Perioperative melatonin secretion in patients undergoing coronary artery bypass grafting
. Anesthesia & Analgesia 2002;94(5):1085-91. Pubmed ID=11973167 more... Govindaswamy S, Chandler J, Latimer R, Vuylsteke A. Management of the patient with coagulation disorders. Current Opinion in Anaesthesiology 2002;15(1):19-25. Pubmed ID=17019180 more... Vuylsteke A, Davidson HJ, Ho WS, Ritchie AJ, Callingham BA, White R, Hiley CR. Effect of the blood substitute diaspirin crosslinked hemoglobin in rat mesenteric and human radial collateral arteries. Journal of Cardiovascular Pharmacology 2001;37(4):394-405. Pubmed ID=11300652 more... Borland C, Mist B, Zammit M, Vuylsteke A. Steady-state measurement of NO and CO lung diffusing capacity on moderate exercise in men. Journal of Applied Physiology 2001;90(2):538-44. Pubmed ID=11160052 more... Latimer MD, Callingham BA, Vuylsteke A. A comparison of the inotropic effects of milrinone and piroximone. Annals of Cardiac Anaesthesia 2001;4(1):17-20. Pubmed ID=17851157 more... Rozario C, Vuylsteke A. Synthetic haemoglobins: start of a story. Innovation et technologie en biologie et médecine 2001;22(Suppl1):49-53. Nashef SAM, Roques F, Vuylsteke A, Keogh BE. Contrôle-qualité par les chirurgiens cardaiques britanniques: du simple dénombrement à la vigilance active. Journal de Chirurgie Thoracique et Cardio-Vasculai 2001;V(2):82-6. Vuylsteke A, Mills RJ, Crosbie AE, Burns TI, Latimer RD. Increased pre-operative platelet counts are a possible predictor for reduced sensitivity to heparin. British Journal of Anaesthesia 2000;85(6):896-8. Pubmed ID=11732526 more... Vuylsteke A, Milner Q, Ericsson H, Mur D, Dunning J, Jolin-Mellgård A, Nordlander M, Latimer R. Pharmacokinetics and pulmonary extraction of clevidipine, a new vasodilating ultrashort-acting dihydropyridine, during cardiopulmonary bypass. British Journal of Anaesthesia 2000;85(5):683-9. Pubmed ID=11094580 more... Ritchie AJ, Hartshorn S, Crosbie AE, Callingham BA, Latimer RD, Vuylsteke A. The action of diaspirin cross-linked haemoglobin blood substitute on human arterial bypass conduits. European Journal of Cardiothorac Surgery 2000;18(2):241-5. Pubmed ID=10925237 more... Vuylsteke A, Feneck RO, Jolin-Mellgård A, Latimer RD, Levy JH, Lynch C 3rd, Nordlander ML, Nyström P, Ricksten SE. Perioperative blood pressure control: a prospective survey of patient management in cardiac surgery. Journal of Cardiothoracic & Vascular Anesthesia 2000;14(3):269-73. Pubmed ID=10890479 more... Nandate K, Vuylsteke A, Ratsep I, Messahel S, Oduro-Dominah A, Menon DK, Matta BF. Effects of isoflurane, sevoflurane and propofol anaesthesia on jugular venous oxygen saturation in patients undergoing coronary artery bypass surgery. British Journal of Anaesthesia 2000;84(5):631-3. Pubmed ID=10844841 more... Crosbie AE, Vuylsteke A, Ritchie AJ, Latimer RD, Callingham BA. Inhibitory effects of glibenclamide on the contraction of human arterial conduits used in coronary artery bypass surgery. Journal of Pharmacy & Pharmacology 2000;52(3):333-40. Pubmed ID=10757423 more... Nandate K, Vuylsteke A, Crosbie AE, Messahel S, Oduro-Dominah A, Menon DK. Cerebrovascular cytokine responses during coronary artery bypass surgery: specific production of interleukin-8 and its attenuation by hypothermic cardiopulmonary bypass. Anesthesia & Analgesia 1999;89(4):823-8. Pubmed ID=10512250 more... Vuylsteke A, Mur D, Gray S, Mackay J, Latimer RD. Transmyocardial Laser Revascularisation: The last hope for refractory angina sufferers? A new challenge for the cardiac anaesthetist
. Annals of Cardiac Anaesthesia 1998;1(1):46-52. Pubmed ID=17827623 Petyaev IM, Vuylsteke A, Bethune DW, Hunt JV. Plasma oxygen during cardiopulmonary bypass: a comparison of blood oxygen levels with oxygen present in plasma lipid. Clinical Science (London) 1998;94(1):35-41. Pubmed ID=9505864 more... Ismail-Zade IA, Vuylsteke A, Ghosh S, Latimer RD. Inhaled nitric oxide and one-lung ventilation in the lateral decubitus position. Journal of Cardiothoracic & Vascular Anesthesia 1997;11(7):926-7. Pubmed ID=9412904 more... Vuylsteke A, Oduro A, Cardan E, Latimer RD. Effect of aspirin in coronary artery bypass grafting. Journal of Cardiothoracic & Vascular Anesthesia 1997;11(7):831-4. Pubmed ID=9412879 more... Milner QJW, Vuylsteke A, Ismail F, Ismail-Zade I, Latimer RD. ICU Resuscitation of the multi-organ donor. A review of the pathophysiology of brain death and the resuscitation of the multi-organ donor. British Journal of Intensive Care 199749-54. Poulton BB, Foubert L, Klinowski J, Latimer RD, Knowles PR, Vuylsteke A. Extraction of nitric oxide and nitrogen dioxide from an oxygen carrier using molecular sieve 5A. British Journal of Anaesthesia 1996;77(4):534-6. Pubmed ID=8942343 more... Vuylsteke A, Rombaut E. [Mise au point: La toxicité de l'acide fluorhydrique]. Louvain Médical 1995;114:739-44. more... Vuylsteke A. L'acide fluorhydrique: un toxique méconnu [Hydrofluoric acid: an unrecognised toxic agent]. Annales Françaises d'Anesthèsie et de Rèanimation 1994;13(3):429-32. Pubmed ID=7992954 more... Pouleur H, van Eyll C, Etienne J, van Mechelen H, Vuylsteke A, Rousseau MF. Effects of long-term xamoterol therapy on the left ventricular mechanical efficiency in patients with ischemic heart disease. Basic Research in Cardiology 1989;84(Suppl 1):157-62. Pubmed ID=2573338 more... Reviews Valchanov K, Vuylsteke A. Pulmonary endarterectomy. European Journal of Anaesthesiology 2006;23(10):815-23. [Review] PMID=16938154 Cohen A, Latimer R, Vuylsteke A. Improving the management of the diabetic patient having heart surgery. Annals of Cardiac Anaesthesia 2003;6(2):149-51. [Review] PMID=17827577 Desilva R, Dunning J, Trull A, Vuylsteke A. A review of ischaemia-reperfusion injury in the cardiorespiratory system. Annals of Cardiac Anaesthesia 2003;6(2):126-31. [Review] PMID=17827573 Senthuran S, Toff WD, Vuylsteke A, Solesbury PM, Menon DK. Implanted cardiac pacemakers and defibrillators in anaesthetic practice. British Journal of Anaesthesia 2002;88(5):627-31. [Review] PMID=12066997 Leonard IE, Vuylsteke A. Acute Normovolaemic Haemodilution and Cardiac Surgery - current opinion and controversies. Annals of Cardiac Anaesthesia 2000;3(2):19-24. [Review] PMID=17848767 Ahmed AB, Latimer RD, Vuylsteke A. Cardiovascular pharmacology: new drugs and new indications. Current Opinion in Anaesthesiology 2000;13(1):5-13. [Review] PMID=17016273 Vuylsteke A. Fundamentals of chirality. Acta Anaesthesiologica Belgica 2000;51(2):113-7. [Review] PMID=11000904 Vuylsteke A, Wallwork J. The heart-transplanted patient in the intensive care unit: last news before the millennium. Current Opinion in Critical Care 1999;5(5):422-6. [Review] PMID= Ahmed AB, Crosbie AE, Latimer RD, Vuylsteke A. Blood substitutes - the current state of the art. Annals of Cardiac Anaesthesia 1999;2(2):4-11. [Review] PMID=17846484 Editorials Mulavisala P, Vuylsteke A, Latimer R. Gene therapy in the management of cardiovascular diseases. Annals of Cardiac Anaesthesia 2001;4(1):4-6. [Editorial] PMID=17851154 Case Reports Leeman MF, Vuylsteke A, Ritchie AJ. Lithium-induced nephrogenic diabetes insipidus after coronary artery bypass. Annals of Thoracic Surgery 2007;84(2):656-7. [Case-Report] PMID=17643658 Sidery M, Cahir J, Screaton NJ, Vuylsteke A. Computed tomography reveals an unusual complication in a patient having undergone coronary artery bypass surgery. Journal of Cardiothoracic & Vascular Anesthesia 2004;18(5):668-70. [Case-Report] PMID=15578485 Murali B, Drain A, Seller D, Dunning J, Vuylsteke A. Pulmonary thromboendarterectomy in a case of hereditary stomatocytosis. British Journal of Anaesthesia 2003;91(5):739-41. [Case-Report] PMID=14570800 Chandler J, Grixti K, Dunning J, Vuylsteke A. An unusual chest radiograph after pulmonary thromboendarterectomy. Journal of Cardiothoracic & Vascular Anesthesia 2002;16(2):253-4. [Case-Report] PMID=11957181 Sharma R, Vuylsteke A. An unusual postoperative pulmonary complication. Journal of Cardiothoracic & Vascular Anesthesia 2000;14(5):615-6. [Case-Report] PMID=11052451 Letters Ramkumar KR, Vuylsteke A. Antihypertensives and angioedema. Anaesthesia 2004;59(3):283-9. [Letter] PMID=15310361 Vuylsteke A, Gerrard C. Reducing blood transfusion. BMJ 's cover and headline exaggerated importance of study's findings. British Medical Journal 2002;325(7365):655. [Letter] PMID=12242182 Satchithananda DK, Stoica SC, Smith S, Woods MJ, Vuylsteke A, Sharples L, Wallwork J, Parameshwar J, Large SR. Empirical supportive therapy in the hypotensive donor - best guess or worst option?. Journal of Heart & Lung Transplantation 2001;20(2):255. [Letter] PMID=11250512 Kuzumi E, Vuylsteke A, Guo X, Menon DK. Serum S100 protein as a marker of cerebral damage during cardiac surgery. British Journal of Anaesthesia 2000;85(6):936-7. [Letter] PMID=11732538 Vuylsteke A, Mur D, Latimer RD, Oduro A, Callingham BA. Myocardial effect of propofol infusions in humans: more questions than answers. Journal of Cardiothoracic & Vascular Anesthesia 1997;11(2):264. [Letter] PMID=9106005 Poulton BB, Foubert L, Klinowski J, Latimer RD, Knowles PR, Vuylsteke A. Extraction of nitric oxide and nitrogen dioxide using molecular sieve 5A. British Journal of Anaesthsia 1997;78(3):343-4. [Letter] PMID=9135329 Edited Books Klein A, Vuylsteke A, Nashef SAM (Eds). Core Topics in Cardiothoracic Critical Care. Cambridge: University Press. 2008. [ISBN 978-0-521-87283] Chapters Lin E, Vuylsteke A. Pulmonary hypertension. In: Klein A, Vuylsteke A, Nashef SAM (Eds) Core Topics in Cardiothoracic Critical Care. Cambridge: University Press. 2008. pp174-9. [ISBN 978-0-521-87283] Dawson AJ, Vuylsteke A. Invasive ventilation. In: Klein A, Vuylsteke A, Nashef SAM (Eds) Core Topics in Cardiothoracic Critical Care. Cambridge: University Press. 2008. pp189-95. [ISBN 978-0-521-87283] Webb ST, Vuylsteke A. Renal protection and cardiac surgery. In: Klein A, Vuylsteke A, Nashef SAM (Eds) Core Topics in Cardiothoracic Critical Care. Cambridge: University Press. 2008. pp223-9. [ISBN 978-0-521-87283] DeSilva RJ, Vuylsteke A. Inflammatory response to cardiopulmonary bypass. In: Mackay JH, Arrowsmith JE (Eds) Core Topics in Cardiac Anaesthesia. London: Greenwich Medical Media. 2004. pp271-274. [ISBN 1-841101-33-8] Gardner AI, Dunning J, Vuylsteke A. Anesthesia for pulmonary thromboendarterectomy. In: Arrowsmith JE, Simpson J (Eds) Problems in Anesthesia: Cardiothoracic Surgery. London: Martin Dunitz. 2002. pp227-235. [ISBN 1-84184-138-2] Wilson WC, Vuylsteke A. Anaesthesia for pulmonary thrombo-endarterectomy. In: Ghosh S, Latimer RD (Eds) Thoracic Anaesthesia. Principles and Practice. Oxford: Butterworth-Heinemann. 1999. pp223-234. [ISBN 0-7506-4062-6] Wilson WC, Vuylsteke A. Anaesthesia for pulmonary thrombo-endarterectomy. In: Ghosh S, Latimer RD (Eds) Thoracic Anaesthesia. Principles and Practice. Oxford: Butterworth-Heinemann. 1999. pp223-234. [ISBN 0-7506-4062-6] Pouleur H, vanEyll C, Etienne J, Van Mechelen H, Vuylsteke A, Rousseau MF. Effects of long-term Xamoterol Therapy on the Left Ventricular Mechanical Efficiency in Patients with Ischemic Heart Disease. In: Just H, Holubarsch Ch, Scholz H (Eds) Inotropic Stimulation and Myocardial Energetics. New York: Steinkopff Verlag Darmstadt, S. 1989. pp. [ISBN 3798508151] Abstracts Ali Z, Lim E, Akouwah E, Ahmed I, Zadeh RM, Gerrard C, Vuylsteke A, Ali A, Foweraker J, Tsui S. Allogenic blood transfusion does not predispose to postoperative infection after surgery: a prospective observational study. British Journal of Surgery 2003;90(Suppl 1):141-2. [Abstract] [Presented at: Reichenberger F, Pepke Zaba JP, Hodgkins D, Vuylsteke A, McNeill K, Dunning J. Outcome after pulmonary thromboendarterectomy for chronic thromboembolic pulmonary hypertension. Thorax 2002;57(Suppl 3):S25. [Abstract] [Presented at: British Thoracic Society Winter Meeting 2002
Pulmonary thromboendarterecomy (PTE) is the treatment of choice in chronic thromboembolic pulmonary hypertension (CTEPH) with proximal vascular obstructions. However PTE is associated with a significant perioperative risk. Over the last 5 years, 100 patients (50 male, 50 female, mean age 53 (18–81) years) underwent PTE at Papworth Hospital. 71 patients survived the procedure, whereas 29 died postoperatively: 10 due to reperfusion oedema, ARDS, or bronchopulmonary infections despite significant improved haemodynamics, 12 had incomplete clearance of vascular obstruction with additional peripheral vascular obstructions, 3 were misdiagnosed preoperatively (PPH, peripheral CTEPH, advanced pulmonary artery sarcoma). Four patients developed surgical complications. The quartile distribution of the outcome is shown below. Evaluating preoperative factors that influenced perioperative outcome, the surviving patients had a significantly higher 6 minute walking distance (268 v 194 metres, p<0.01), and higher cardiac index (1.8 v 1.5 l/min/qm, p<0.01) compared to the non-survivors, whereas right atrial and pulmonary artery pressures were similar in both groups. At our institution, experience within the recently established PTE programme shows a learning curve associated with a significant improvement in the postoperative outcome in this high risk patient population. |
